Senior Software Engineer, Full Stack

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. This role strongly prefers candidates located in the Boston area with the ability to regularly commute to our Seaport headquarters. Due to the nature of this role, candidates should expect to support U.S. Government customers. Candidates must have the ability to obtain and maintain a U.S. security clearance per business requirements. In connection therewith, candidates must be willing to undergo a background investigation and meet eligibility requirements. Clearance sponsorship will be available. Candidates who currently hold an active or recently inactive U.S. Government security clearance are encouraged to apply. Ginkgo Biosecurity is building next-generation biosecurity infrastructure to help governments and partners detect, attribute, and deter biological threats. Our mission extends across public health, national security, and global defense, ensuring nations can rapidly identify dangerous pathogens, understand where threats originate, and respond with confidence. We are seeking a Senior Full-Stack Software Engineer to join the Biosecurity engineering team. Th [... source excerpt omitted ...] a technical expert but also a forward-thinker who embraces AI-augmented development and maintains a 'deploy-with-confidence' culture through rigorous CI/CD and automated testing You will work across the stack—from backend services and data pipelines to user-facing web applications—building reliable, scalable systems that turn complex biological data into actionable insights. Responsibilities Develop high-performance full-stack applications that translate complex biological data and operational needs into intuitive software using Python and modern JavaScript frameworks Champion an AI-first mindset, leveraging generative AI tools and LLM-based assistants to accelerate feature [... source excerpt omitted ...] design reviews and providing critical feedback on software modularity, while upholding rigorous standards for documentation, observability, and long-term maintainability Support production systems by monitoring performance, troubleshooting issues, and continuously improving reliability, including on-call support and triage in off hours Minimum Requirements 6-8+ years of professional software engineering experience, with significant full-stack development work, including ownership of complex systems and cross-team technical initiatives. Strong proficiency in Python for backend development (our primary programming language). Experience building and consuming APIs (REST and/or G