Senior Manufacturing Systems Engineer
AI summary of the role
Senior Manufacturing Systems Engineer at Amgen's most technologically advanced drug substance manufacturing plant in Holly Springs, NC.
No longer in the current catalog. Last included 2026-09-09. Check the employer’s posting for availability.
What you’ll do
- Work with process SMEs to understand key process requirements and transform them into digital automated solutions.
- Lead and support functional area projects focused on improving process equipment/utilities/facilities and large capital projects to integrate new drug substance manufacturing technologies.
- Lead and support new product introductions (NPI) by performing automation engineering assessments and implementing automation system configuration changes.
- Provide clear documentation for delivered solutions and processes; support computerized systems validation processes in a GxP environment.
What you’ll bring
- Doctorate degree OR Master's degree and 2 years of Manufacturing Process automation/Information system experience OR Bachelor's degree and 4 years experience.
- Direct knowledge of automation design and experience in process control engineering with GMP biopharmaceutical production equipment/systems.
- Extensive understanding of programming, design, installation, and lifecycle management of manufacturing process controls and automation.
- Experience with Emerson Delta-V DCS system, Process Control Network design, and Process Control System Virtual Infrastructure.
Technologies
Emerson Delta-V · Rockwell FactoryTalk · Rockwell PLC · Aveva PI Data Historian · Kneat · GAMP · ANSI/ISA-S88 · ANSI/ISA-S95 · MES · PCS
About Amgen
Biotech company that discovers, manufactures, and delivers human therapeutics across oncology, inflammation, general medicine, and rare disease for millions of patients globally.
Public · 5000+ people
Source and classification
Internal deployment & tooling · Evidence for this classification:
of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Manufacturing Systems Engineer What you will do Let’s do this. Let’s change the world. In this vital role you will be part of Amgen's most technologically advanced drug substance manufacturing plant. The facility continues to expand in size and advance with embedded new technologies and industry 4.0 capabilities facility wide. As a Senior Manufacturing Systems Engineer, you will: Work with process subject matter experts (SMEs) to understand key process requirements and transform them into digital automated solutions. Collaborate with business partners to understand how automation can improve workflow and productivity. Synthesize requirements from clients, customers or end-users to develop the best automation solutions. Lead and support functional area projects focused on
More from the job description
Career Category Information Systems Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Manufacturing Systems Engineer What you will do Let’s do this. Let’s change the world. In this vital role you will be part of Amgen's most technologically advanced drug substance manufacturing plant. The facility continues to expand in size and advance with embedded new technologies and industry 4.0 capabilities facility wide. As a Senior Manufacturing Systems Engineer, you will: Work with p [... source excerpt omitted ...] equirements and transform them into digital automated solutions. Collaborate with business partners to understand how automation can improve workflow and productivity. Synthesize requirements from clients, customers or end-users to develop the best automation solutions. Lead and support functional area projects focused on improving process equipment/utilities/facilities as well as large/sophisticated capital projects to integrate new drug substance manufacturing technologies into the facility Lead and support new product introductions (NPI) or new technology introductions by performing automation engineering assessments, implementing automation system configuration changes and sup [... source excerpt omitted ...] better, and more cost effectively What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek will have these qualifications. Basic Qualifications: Doctorate degree OR Master's degree and 2 years of Manufacturing Process automation/Information system experience OR Bachelor's degree and 4 years Manufacturing Process automation/Information system experience OR Associate's degree and 8 years of Manufacturing Process automation/Information system experience OR High school diploma / GED and 10 years of Manufacturing Process automation/Information system experience Preferred Qualifications: Demonstrable experience
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